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I don't want to start a bigI don't want to start a big Creationism argumement. However, increasing a genome by 10x isn't that hard. There are mechanisms where DNA is copied. Over time, one version of the copy is modified. Perhaps the chunk of DNA was for making a gall bladder. The organism grows two. One of the two morphs into a related function. A million years later, a never before seen functioning organ is there. Three doublings gets you 8x. Oh, and a million years is a long time. Especially for mice which have a new generation every year. An organism gets a bigger genome if there is an evolutionary advantage. If there is such an advantage, it doesn't take long to happen. Information theory supports Evolution. Modern medicine depends on it. If it didn't work, i'd be dead. Cogito, ergo sum. Sum, ergo Evolution works.