that would require that each team has a full roster and stats need to be compiled for each player in every game.  That would be a lot of work.

However, I think that if the schedule gets put out right before the book that doing a pick'em league to be submitted before the book is released would be a better solution.
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it would have to come with some huge spoiler warnings for those not yet finished with the book or those who are waiting to listen to it via cast.
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That's a kick-ass idea!